Table 4.

Comparison of the simulated and fitted parameters for analysis by Equation (6)

Parameter	Response 1		Response 2
	Simulated	Fitted	Simulated	Fitted
E max	1.67 ± 0.07	1.68 ± 0.07	44.0 ± 4.8	45.8 ± 5.7
bkgd	0.95 ± 0.04	0.94 ± 0.04	5.20 ± 0.47	4.60 ± 0.83
logχ 1	−0.30 ± 0.06	−0.28 ± 0.05	−0.06 ± 0.06	−0.09 ± 0.06
logχ 2	−0.93 ± 0.08	−0.86 ± 0.08	−0.62 ± 0.06	−0.65 ± 0.09
logε A	1.77 ± 0.05	1.69 ± 0.09	1.60 ± 0.07	1.60 ± 0.12
logε B	−0.96 ± 0.05	−0.93 ± 0.10	−2.00 ± 0.13	−1.94 ± 0.19
logε C	0.93 ± 0.07	0.86 ± 0.08	−0.45 ± 0.08	−0.45 ± 0.09
logε D	1.39 ± 0.04	1.34 ± 0.08	2.33 ± 0.10	2.35 ± 0.23
pK aA	−0.56 ± 0.05	−0.58 ± 0.06	−0.35 ± 0.10	−0.36 ± 0.10
pK aB	−2.07 ± 0.06	−2.07 ± 0.08	−1.87 ± 0.09	−1.86 ± 0.07
pK aC	−1.04 ± 0.03	−1.08 ± 0.03	−0.96 ± 0.08	−0.94 ± 0.10
pK aD	0.08 ± 0.6	0.07 ± 0.05	0.06 ± 0.08	0.07 ± 0.21
log(n)	0.16 ± 0.04	0.19 ± 0.02	−0.15 ± 0.04	−0.16 ± 0.06
log(ε/K a)A	2.33 ± 0.07	2.27 ± 0.09	1.96 ± 0.15	1.96 ± 0.15
log(ε/K a)B	1.11 ± 0.09	1.13 ± 0.12	−0.13 ± 0.14	−0.08 ± 0.17
log(ε/K a)C	1.97 ± 0.07	1.94 ± 0.08	0.51 ± 0.11	0.49 ± 0.13
log(ε/K a)D	1.32 ± 0.07	1.27 ± 0.09	2.27 ± 0.17	2.28 ± 0.15

Values are the mean ± SEM of the six simulated sets of parameters. Subscripts A–D refer to the four ligands. Subscripts 1 and 2 refer to the different receptor expression levels.