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. 2018 Apr 20;42(1):141–148. doi: 10.3892/ijmm.2018.3637

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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miR-222 expression is highest in the HepG2 cell line. (A) Among 3 human liver cancer cell lines, including HCC-LM3, SMCC7721 and HepG2, the latter had the highest level of miR-222. Therefore, HepG2 cells were used in the subsequent experiments. (B) No significant difference in the expression levels of miR-222 was detected between the control group and miR-NC inhibitor group, but it was notably decreased in the miR-222 inhibitor group. ^**P<0.01 miR-222 inhibitor group vs. NC group. miR, microRNA; NC, negative control.