Figure 3.

miR-222 inhibitor increases the apoptotic rate of HepG2 cells and decreases their proliferation. No obvious changes in HepG2 cell apoptosis or proliferation were identified between the control and the miR-NC inhibitor group. (A and B) Compared with HepG2 cells in the control group and miR-NC inhibitor group, the apoptotic rate was significantly increased by treatment with miR-222 inhibitor, while (C) the proliferation ability was significantly reduced by miR-222 inhibitor. ^**P<0.01 miR-222 inhibitor group vs. NC group. miR, microRNA; NC, negative control; PI, propidium iodide; Con, control; FITC, fluorescein isothiocyanate; OD, optical density; Q, quadrant.