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. 2018 Apr 24;42(1):381–391. doi: 10.3892/ijmm.2018.3639

Figure 8.

Figure 8

Rab10 is a direct target of miR-378a-3p in the esophageal squamous cell carcinoma cells. (A) Prediction of the binding between miR-378a-3p and Rab10 using TargetScan software. (B) A dual-luciferase reporter assay was performed to verify the binding of miR-378a-3p with Rab10. (C) Reverse transcription-quantitative polymerase chain reaction and (D) western blot assays were performed to detect the levels of Rab10 in EC109 and KYSE150 cells treated with miR-378a-3p mimics and miR-378a-3p inhibitors. For each experiment, n=3 (*P<0.05, vs. control, **P<0.01, vs. control). miR, microRNA; NC, negative control; 3′UTR, 3′-untranslated region; WT, wild-type; MUT, mutated.