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. 2018 Mar 27;42(1):322–330. doi: 10.3892/ijmm.2018.3592

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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LIPUS enhances SDF-1 expression in PDLSCs. (A) Effects of different intensities of LIPUS treatment on the mRNA expression and protein secretion of SDF-1, as measured by RT-qPCR and ELISA respectively. (B) Effects of AMD3100 antagonist on the mRNA expression and protein secretion of SDF-1, as measured by RT-qPCR and ELISA respectively. (C) mRNA expression of SDF-1 in different treatments. (D) SDF-1 secretion following blocking of SDF-1/CXCR4 signaling as demonstrated by ELISA. ^*P<0.05, ^**P<0.01, ^***P<0.005 and ^****P<0.001 vs. control group; ^###P<0.005 and ^####P<0.001 vs. LIPUS group. LIPUS, low-intensity pulsed ultrasound; SDF-1, stromal cell-derived factor-1; PDLSCs, periodontal ligament stem cells; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; ns, not significant.