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. 2018 Mar 29;42(1):115–122. doi: 10.3892/ijmm.2018.3598

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Copyright: © Gong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Cytotoxic effect of TG on cultured podocytes. (A) Cell counting kit-8 assay results of MPCs following treatment with different TG concentrations. At a TG concentration of 2.5 µg/ml, cell viability was significantly decreased (P<0.01; red arrow). (B) Apoptotic rates of MPCs following treatment with different TG concentrations, as detected by the Annexin V/propidium iodide assay. The percentage of apoptotic cells increased significantly at a TG concentration of 2.5 µg/ml (P<0.001; red arrow). Data are presented as the mean ± standard deviation (n=3). ^**P<0.01 and ^***P<0.001 vs. 0 µg/ml group. MPCs, mouse podocyte cells; TG, tripterygium glycoside.