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. 2018 Mar 22;42(1):237–247. doi: 10.3892/ijmm.2018.3585

Figure 6.

Figure 6

Fisetin-improves acute otitis media triggered by lipopolysaccharides (LPS) is associated with TXNIP and MAPKs signaling pathways. Western blot assays were conducted to assess (A) TXNIP, (B) NLRP3, (C) ASC, (D) cleaved caspase-1, (E) phosphorylated ERK1/2 and (F) phosphorylated p38 levels in the middle ear of mice after LPS treatment. Data are expressed as the mean ± SEM (n=10). *p<0.05, **p<0.01 and ***p<0.001 vs. the control (Con) group; +p<0.05, ++p<0.01 and +++p<0.001 vs. the LPS group.