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. 2018 Mar 22;42(1):237–247. doi: 10.3892/ijmm.2018.3585

Figure 7.

Figure 7

Fisetin ameliorates the acute otitis media in the middle ear of mice through TXNIP/NLRP3 suppression. The immunofluorescent analysis was used to analyze (A) TXNIP and (B) NLRP3 levels in the middle ear sections with the specific antibodies. The quantification of influorescent intensity is dispalyed. (C) TXNIP and (D) NLRP3 mRNA levels were calculated through RT-qPCR assays. Data are expressed as the mean ± SEM (n=10). *p<0.05, **p<0.01 and ***p<0.001 vs. the control (Con) group; +p<0.05, ++p<0.01 and +++p<0.001 vs. the lipopolysaccharides (LPS) group.