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. 2018 Mar 26;8:5197. doi: 10.1038/s41598-018-23558-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression profiles of taxol-biosynthesis-related genes in six overexpression cell lines. Expression of DBAT and T5H genes, which encoded taxol biosynthesis enzymes, were certificated to be controlled by W-boxes in their promoters. Promoter of TcERF12 and TcERF15, which were regulators of taxol biosynthesis, also contained W-boxes. The expression levels of taxol-biosynthesis-related genes were determined by qRT-PCR. Actin was used as reference gene, and each experiment was conducted three repeats.