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. 2018 Mar 26;8:5202. doi: 10.1038/s41598-018-23450-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Result of experimental conditions in SHR, WKY, and WIS: Average and standard error of the mean (SEM) of slope, intercept and mPower parameters are depicted as bar and error bar. The marks ‘*’ and ‘#’ indicate the results of the statistical significance test, the one-tailed t-test, between the vehicle and other specific pharmacological agent administration for which the significant levels are 0.05 and 0.01, respectively. Positive and negative significance are colour-coded using black and red, respectively.