Table 1.
Phenotype of Cebpb and Runx2 genetically modified mice. (F2:129 Sv/C57BL/6) with aberrant incisors at 3 months after birth. The table shows penetrance, location, and characteristics of aberrant incisors.
Cebpβ+/+Runx2+/+ (F2) |
Cebpβ+/+Runx2+/−(F2) |
Cebpβ−/−Runx2+/+ (F2) |
Cebpβ−/−Runx2+/− (F2) | |
---|---|---|---|---|
Penetrance | 0/4 (0%) | 0/9 (0%) | 5/8 (62.5%) | 4/12 (33%) |
Location of aberrant incisor | ||||
Maxilla | 0(0%) | 0(0%) | 5(100%) | 4(100%) |
Mandible | 0(0%) | 0(0%) | 0(0%) | 0(0%) |
Unilateral | 0(0%) | 0(0%) | 1(20%) | 4(100%) |
Bilateral | 0(0%) | 0(0%) | 4(80%) | 0(0%) |
Characteristics of aberrant incisors | ||||
Short incisor | 0(0%) | 0(0%) | 3(60%) | 0(0%) |
With supernumerary teeth | 0(0%) | 0(0%) | 2(40%) | 4(100%) |