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In vivo safety. A) Body weights, B) survival rates, and C) ex vivo histological analyses of main organ sections from K7 osteosarcoma‐xenografted mice after treatment with PBS as control, free DOX plus CDDP, or CDDP3.3HANG/DOX5.4. Magnification: 200×. Scale bar: 200.0 µm. Data are presented as a mean ± SD (n = 7 for panel (A), n = 5 for panel (B); *P < 0.05, ***P < 0.001).
