Figure 7.

Respirometry data for islets obtained from vehicle (Veh)‐ or mitoQ MQ)‐treated mice. (A) Oxygen consumption rate (OCR) measurements over time and after additions of glucose, oligomycin, or rotenone (Rot) plus antimycin A (Anti A). (B) Data of (A) expressed as percent basal OCR. (C‐F) OCR component analyses expressed per well as basal OCR (C), glucose‐stimulated‐OCR (D), OCR directed at ATP production (E) and nonmitochondrial OCR (F). (G‐J) Parameters measured in (C‐F), respectively, but normalized to DNA content. Data in all panels represent mean ± SE, n = 6 islet preparations for each group. P values were determined by 2‐tailed, unpaired t test