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. 2018 Apr 14;7(6):487–494. doi: 10.1002/sctm.17-0258

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© 2018 The Authors stemcellstranslationalmedicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Prevention of corneal scarring by CSSC embedded in CCG. (A): Most corneal wounds covered with CCG healed with scars visible at 14 days. (B): None of the wounds treated with CCG containing CSSC cells showed scarring at 14 days. (C): Wounded corneas exhibited 5/6 scarred corneas with CCG‐only treatment but 0/10 corneas showed visible scarring when treated with CCG + CSSC. Contingency analysis (Fisher's Exact Test) of these data indicated high level of significance (p = .0014). Abbreviations: CCG, compressed collagen gel; CSSC, corneal stromal stem cells.