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. 2018 Apr 14;109(5):1723–1730. doi: 10.1111/cas.13565

Figure 4.

Figure 4

Proposed model for how CD169+ macrophages enhance anti‐tumor immunity. (1) Dead tumor cells are delivered to draining lymph nodes via lymphatic vessel. (2) CD169+ macrophages in the regional lymph nodes capture dead tumor cells and present the tumor antigen to CD8+ T cells. (3) The activated CD8+ T cells travel to the bladder tumor and suppress their proliferation