Figure 1.

NR2F1‐AS1 was up‐regulated in oxaliplatin‐resistant hepatocellular carcinoma (HCC) tissue and cell lines. A, Heat map shows the representative dysregulated lncRNA with more than fourfold changes. Red symbol presented the high‐expression RNAs. Green symbol presents the low‐expression RNAs. B, NR2F1‐AS1 was up‐regulated in 47 cases of oxaliplatin‐resistant HCC tissue compared with oxaliplatin‐sensitive tissue samples. C, RT‐PCR showed that NR2F1‐AS1 was up‐regulated in human oxaliplatin‐resistant HCC cell lines (Huh7/OXA, HepG2/OXA) compared with parental cell lines. Lo‐2 was the normal liver cells. Data are presented as the mean ± SD. *P < .05, **P < .01 compared to control group