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. 2018 Mar 13;22(6):3167–3182. doi: 10.1111/jcmm.13597

Figure 1.

Figure 1

The combined action of DEX and miR‐140‐5p suppresses the Wnt/β‐catenin signalling pathway detected by RT‐qPCR and Western blot analysis. Notes: A, Cartogram of miR‐140‐5p expression and mRNA expressions of Wnt/β‐catenin signalling pathway‐related genes (Wnt1, β‐catenin, TCF‐4 and E‐cadherin) of rats among eight groups; B, Cartogram of protein expressions of Wnt/β‐catenin signalling pathway‐related genes (Wnt1, β‐catenin, TCF‐4 and E‐cadherin) of rats among eight groups; C, Protein bands of Wnt/β‐catenin signalling pathway‐related proteins (Wnt1, β‐catenin, TCF‐4 and E‐cadherin) of rats among eight groups; D, Immunofluorescence staining image among eight groups *, P < .05, compared with the sham group; #, P < .05, compared with the model group; &, P < .05, compared with the DEX group; three surviving rats were randomly selected from each group; the experiment was repeated 3 times; DEX, dexmedetomidine; NC, negative control; miR‐140‐5p, microRNA‐140‐5p; TCF‐4, T cell factor 4