Table 4.
Groups (n = 5) | MAP (mm Hg) | LVESP (mm Hg) | LVEDP (mm Hg) | +dP/dt (mm Hg/s) | −dP/dt (mm Hg/s) |
---|---|---|---|---|---|
Sham group | 140.8 ± 7.2 | 121.1 ± 10.6 | 17.7 ± 3 | 3735.7 ± 434.5 | −3023.5 ± 369.3 |
MI group | 76.5 ± 7.1* | 86.7 ± 10.8* | 40.6 ± 9.6* | 1604.2 ± 289.0* | −1259.1 ± 110.6* |
LTS group | 116.4 ± 9.8** , *** | 105.7 ± 6.1** , *** | 26.0 ± 7.4** , *** | 2609.2 ± 284.8** , *** | −2127.5 ± 202.7** , *** |
HTS group | 122.9 ± 9.2** , * | 116.8 ± 9.4** , * | 19.2 ± 3.2** , * | 3028.2 ± 655.7** , * | −2485.5 ± 500.8** , * |
LPS | 62 ± 7.6** | 71.8 ± 6.3** | 53.3 ± 3.8** | 1002.9 ± 151.3** | −665.6 ± 61.2** |
T + LPS | 119.05 ± 9.1*** | 109.1 ± 9.2*** | 23.95 ± 2.9*** | 2982.01 ± 168.66*** | −2255.2 ± 243.8*** |
LTS + LPS group | 89.7 ± 9.9 | 97.1 ± 8.9 | 32.1 ± 3.5 | 2015.6 ± 235.6 | −1798.5 ± 511.2 |
HTS + LPS group | 99.6 ± 8.3 | 103.3 ± 9.1 | 23.9 ± 2.8 | 2468.9 ± 351.8 | −2006.2 ± 341.9 |
MI, myocardial infarction; LTS, low‐dose tanshinone IIA; HTS, high‐dose tanshinone IIA; LPS, Lipopolysaccharide; MAP, mean arterial pressure; LVEDP, left ventricular end‐diastole pressure; LVESP, left ventricular end‐systolic pressure; +dP/dt, the maximum rate of developed left ventricular pressure; −dP/dt, the maximum rate of left ventricular pressure decay.
* P < .05 compared with the Sham group; **P < .05 compared with the MI group; ***P < .05 compared with the LPS group.