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. 2018 Mar 5;232(6):1031–1037. doi: 10.1111/joa.12800

Figure 1.

Figure 1

Representative sections of short post mortem interval (SPMI) gingival tissues showing hypoxia inducible factor (HIF‐1α) protein expression. (a) Haematoxylin–eosin staining of gingival mucosa showing the oral epithelium (OE), in which the stratum basale (sb), stratum spinoso (ss) and stratum granulosum (sg) and the sub‐oral connective tissues (SCT) are observed (magnification 10 ×; scale bar: 150 μm). (b) HIF‐1α protein is mainly localized in the OE (magnification 10 ×; scale bar: 150 μm). (c) A strong signal of the HIF‐1α protein is detected in the stratum basale (arrow), and it gradually decreased in the mid‐epithelium to finally disappeared in the stratum corneum (arrowhead; magnification 20 ×; scale bar: 50 μm). (d) Cells of the SCT showed a strong signal of HIF‐1α protein (arrow; magnification 100 ×; scale bar: 100 μm). Representative sections of oral medium post mortem interval (MPMI) gingival tissues showing HIF‐1α protein expression. (e) Haematoxylin–eosin staining of gingival mucosa showing the OE and the SCT (magnification 10 ×; scale bar: 150 μm). (f) HIF‐1α protein is localized in the OE (magnification 10 ×; scale bar: 150 μm). (g) HIF‐1α protein is detected in the stratum basale (arrow), and it gradually decreased in the mid‐epithelium (*) and stratum corneum (arrowhead; magnification 20 ×; scale bar: 50 μm). (h) SCT showing cells positive for HIF‐1α immunostaining (arrow; magnification 100 ×; scale bar: 100 μm).