Figure 4.

Comparison of the pharmacokinetics of 4‐borono‐2‐¹⁸F‐fluoro‐phenylalanine (¹⁸F‐FBPA) by different injection protocols. ¹⁸F‐FBPA was injected by bolus injection (A and B), and continuous intravenous infusion (C and D). ¹⁸F‐FBPA was also co‐injected with ¹⁰B‐4‐borono‐L‐phenylalanine (BPA) (250 mg/kg) by continuous intravenous infusion (E and F). Representative PET/computed tomography (CT) images at 50‐60 minutes of the same LN‐229‐bearing SCID mouse (A,C,E). White arrows indicate LN‐229 tumors. Time‐activity curves (n = 3‐4) (B,D,F)