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. 2018 Apr 29;109(5):1428–1446. doi: 10.1111/cas.13552

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© 2018 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Cell apoptosis after long non‐coding RNA (lncRNA) RP11‐552M11.4 mimic and inhibitor plasmid transfection into SKOV3 cells. A, B, Annexin V/propidium iodide (AV/PI) assay showed that cell apoptosis rate was reduced in the lncRNA RP11‐552M11.4(+) group compared with the NC1(+) group, and enhanced in the lncRNA RP11‐552M11.4(−) group compared with the NC2(−) group. C‐F, C‐Caspase3 and Bcl‐2 protein expression also indicated that lncRNA 11‐552M11.4(+) decreased whereas lncRNA 11‐552M11.4(−) increased cell apoptosis compared with NC. Comparison was determined by t test. *P < .05, **P < .01, ***P < .001