Table 3.
Demographic, biochemical, and echocardiographic data
| Controls | ASYMP | LAD | HF | |
|---|---|---|---|---|
| Number | 88 | 53 | 19 | 21 |
| Sex (male/female) | 43/45 | 42/11 | 13/6 | 18/3 |
| Age (years) | 6.0 (1.0–11.4) | 4.0 (1.4–10.2) | 5.9 (3.6–8.8) | 11.0 (4.3–13.5) * |
| Body weight (kg) | 3.9 (3.0–4.7) | 4.8 (4.0–5.5)‡ | 4.5 (4.1–5.4) | 4.6 (4.0–5.4) |
| Heart rate (bpm) | 180 (163–200) | 200 (173–220) | 205 (168–217) | 170 (143–198) |
| Systolic blood pressure (mm Hg) | 130 (145–157) | 142 (132–160) | 136 (126–146) | 127 (105–146) |
| Urea nitrogen (mg/dL) | 24 (21–28) | 26 (22–29) | 26 (24–32) | 36 (31–46)‡# |
| Creatinine (mg/dL) | 1.3 (1.1‐1.5) | 1.4 (1.2‐1.7) | 1.6 (1.3‐1.8) | 1.7 (1.2‐2.0) |
| Thyroxine (µg/dL) | 2.0 (1.7‐2.5) | 2.0 (1.7‐2.7) | 1.7 (1.5‐2.7) | 0.6 (0.9‐2.1) * |
| Echocardiography | ||||
| IVSd (mm) | 4.1 (3.6‐4.6) | 6.5 (5.2–7.1)‡ | 6.1 (5.3–7.3)‡ | 6.4 (5.9‐7.2)‡ |
| LVIDd (mm) | 14.4 (13.0–15.9) | 14.3 (12.0–15.6) | 14.4 (12.8–16.7) | 14.5 (12.4–15.7) |
| LVPWd (mm) | 4.0 (3.5‐4.7) | 5.9 (5.1–6.6)‡ | 7.2 (4.9‐8.2)‡ | 7.0 (6.1–8.9)‡ |
| Relative wall thickness | 0.57 (0.47‐0.67) | 0.85 (0.74‐1.09)‡ | 0.87 (0.72‐1.14)‡ | 0.93 (0.73‐1.17)‡ |
| LA/Ao ratio | 1.3 (1.2‐1.4) | 1.3 (1.2‐1.4) | 2.0 (1.8‐2.5)‡# | 2.1 (1.9‐2.5)‡# |
| E wave (cm/s) | 63.9 (52.7–71.6) | 64.5 (55.2–83.0) | 100.5 (83.1–110.2)‡# | 84.3 (68.4–98.1)† |
Data are expressed as medians (IQR).
Abbreviations: ASYMP, asymptomatic cats without left atrial dilatation; E wave, mitral early diastolic flow; HF, cats with heart failure; IVSd, end‐diastolic intraventricular septum; LA/Ao ratio, left atrium‐to‐aorta ratio; LAD, asymptomatic cats with left atrial dilatation; LVIDd, end‐diastolic left ventricular internal dimension; LVPWd, end‐diastolic left ventricular posterior wall.
*: P < .05 versus healthy controls, †: P < .01 versus healthy controls, ‡: P < .001 versus healthy controls, #: P < .001 versus the ASYMP group.