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. 2018 Apr 17;109(5):1369–1381. doi: 10.1111/cas.13575

Figure 8.

Figure 8

In vivo efficacy of hispidulin in colorectal cancer tumor growth and metastasis. A, Suppression of tumor growth by hispidulin (His) in a xenograft animal model. B, Reduction in tumor weight by hispidulin treatment. C, Repression in expression of provirus integration site for Moloney murine leukemia virus (PIM1), phosphorylated signal transducer and activator of transcription 3 (p‐STAT3), and p‐JAK2 by hispidulin in tumor tissue. D, Decrease in pulmonary metastatic nodules by hispidulin in a xenograft animal model. **P < .01