Table 1.
Frequency table for International Union of Immunological Sciences (IUIS) classification and minimum disease prevalence
| IUIS classification | n (alive patients) | UK prevalence/100 000 |
|---|---|---|
| Autoinflammatory disorders | 25 | 0·04 |
| Combined immunodeficiencies | 329 | 0·50 |
| Complement deficiencies | 559 | 0·85 |
| Defects in innate immunity | 39 | 0·06 |
| Diseases of immune dysregulation | 94 | 0·14 |
| Other well‐defined PIDs | 325 | 0·49 |
| Phagocytic disorders | 177 | 0·27 |
| Predominantly antibody disorders | 2589 | 3·92 |
| Unclassified immunodeficiencies | 160 | 0·24 |
Estimated minimum prevalence data for primary immunodeficiency (PID) in the United Kingdom is based on a national population of 66 029 990 (source: Office for National Statistics).