Figure 6.

Periostin (POSTN) re‐educated the cytokine profiles of THP‐1‐derived macrophages (Mφ). A, THP‐1‐derived macrophages were cocultured with A2780 cells transfected by control and siPOSTN for 24 h, then the transcription of cytokines of THP‐1‐derived macrophages was measured by quantitative RT‐PCR. B, POSTN neutralizing antibody (NAb) or isotype antibodies were added to the conditioned medium of the coculture system for 24 h, then the transcription of cytokines of THP‐1‐derived macrophages was measured by quantitative RT‐PCR. Arg‐1, arginase‐1; CCL, CC chemokine ligand; IL, interleukin; scr, scrambled; TGF‐β, transforming growth factor‐β; TNF‐α, tumor necrosis factor‐α