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. 2018 Feb 12;7(6):e1428157. doi: 10.1080/2162402X.2018.1428157

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 4. — Kaplan-Meier curves from random assignment by treatment group (vaccination or observation) upon stratification of patients according to the lymph node-negative status confirmation (clinical evaluation also called no node dissection (noND) or node dissection (ND)) of (A) relapse-free (RFS), (hazard ratio [HR](ND vs noND^vaccination), 0.50; 95% CI, 0.36 to 0.71; P = 0.0001; HR(ND vs noND^observation), 0.68; 95% CI, 0.49 to 0.95; P = 0.022) (B) distant metastasis free (DMFS), (HR(ND vs noND^vaccination), 0.55; 95% CI, 0.36 to 0.82; P = 0.003; HR(ND vs noND^observation), 0.82; 95% CI, 0.55 to 1.22; P = 0.33) and (C) overall survival (OS), (HR(ND vs noND^vaccination), 0.46; 95% CI, 0.29 to 0.73; P = 0.001; HR(ND vs noND^observation), 0.84; 95% CI, 0.54 to 1.31; P = 0.44).