Figure 2.

Relationship between CCL22 expression and overall survival among patients with gastric cancer in combined data set. Representative images showed that there existed CCL22-positive tumors (A) and CCL22-negative tumors (B) simultaneously. CCL22-positive tumors were associated with a lower rate of 5-year overall survival compared with those with negative CCL22 expression (C) and the result was validated by generating multivariate analysis based on cox proportional hazards regression model containing age, tumor size, tumor grade, tumor stage and CCL22 expression (D). The association between CCL22-positive tumors and a lower rate of 5-year overall survival was independent of pathological tumor grade (E).