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. 2018 Apr 27;27(6):1125–1135. doi: 10.1002/pro.3416

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© 2018 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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GRASP‐Func clustering of 6‐HG known function (light blue) and SG (dark green) proteins. Proteins are represented as nodes. The thickness of each edge shows the degree of similarity between the two connected proteins. PDB IDs for proteins of known function: 1gai, 1ayx, 1lf9, 1ug9 (1a–d); 3qt9, 3qsp (2a–b); 1cem, 1wu4, 1v5c, 1h12 (3a–d); 1clc, 1kfg, 1ksc, 1ia6 (4a–d); 2d5j, 2zzr (5a–b); 2okx, 3w5m, ALR1 (6a–c); 4ufc, 2eac, ALF1, ALF2 (7a–d); 2jf4, TRE1 (8a–b); 2d8l (9); 3ren (10); 1v7x, 2cqs, CDP1 (11a–c); 1h54, NGP1 (12a–b); 1fp3, 2gz6 (13a–b). Each SG protein is numbered based on its Label in Table S12, Supporting Information.