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. 2017 Aug 17;175(12):2219–2230. doi: 10.1111/bph.13957

Figure 2.

Figure 2

Crystal structure of the trimeric human P2X3 receptor channel showing interactions with the competitive antagonist A‐317491 bound to the orthosteric ATP site. Cartoon (left), space fill (centre) and ball‐and‐stick (right) representations are displayed in two orientations. The dashed lines indicate the position of the lipid bilayer. Coordinates from PDB #5SVR (Mansoor et al., 2016) viewed in JSmol.