Table 1.
Plasma and brain levels of oxycodone following prolonged (6 days) treatments
Oxycodone treatment | Low | Medium | High |
---|---|---|---|
Plasma concentration (ng·mL−1) | 81 ± 8 | 284 ± 147 | 1670 ± 635 |
Brain level (ng·g−1) | 248 ± 126 | 426 ± 87 | 1703 ± 665 |
In all cases n = 6, except the plasma concentration following medium oxycodone treatment where n = 5 (one sample lost)