. Author manuscript; available in PMC: 2019 Jun 15.

Published in final edited form as: Stat Med. 2018 Feb 26;37(13):2108–2119. doi: 10.1002/sim.7627

Table 2.

Results from 100 simulations under the three level mixed effects location scale model : Variance Model Parameters

Model	α^intercept = 0.3			α^subj = 0.2			α^wave = 0.1

	Bias	AIW	COV	Bias	AIW	COV	Bias	AIW	COV
Two Level MRM HV	0.6109	0.0608	1	−0.0609	0.0567	19	−0.0096	0.0712	16
Two Level MLS	0.5350	0.1499	5	−0.0730	0.1439	49	0.0071	0.1106	17
Three Level MRM HV	0.2410	0.0605	5	−0.0004	0.0570	47	−0.0402	0.0672	12
Three Level MLS	−0.0038	0.8596	97	0.0040	0.2081	95	−0.0155	0.9114	99

AIW: average 95% credible interval; COV: 95% coverage rate out of 100 simulations.