TABLE 2.

Characteristics of 25 patients enrolled on study

Characteristics		Number of patients (%)
Median age at study enrollment (years; range)	11.9 (2.9 to 21.3)
Gender
Male		10 (40%)
Female		15 (60%)
Race/ethnicity
Caucasian		17 (68%)
African-American		3 (12%)
Hispanic		5 (20%0
Histologic diagnoses
Anaplastic astrocytoma		3 (12%)
Glioblastoma		10 (40%)
High-grade glioma		4 (16%)
No histologic confirmation		8 (32%)
Previous RT		25 (100%)
Previous regimens of chemotherapy
0		2 (8%)
1		16 (64%)
2		5 (20%)
≥ 3		2 (8%)

Of note, 11 patients had a radiologic diagnosis of diffuse intrinsic pontine glioma

Three patients with diffuse intrinsic pontine glioma had histologic confirmation at biopsy (n=2) or at autopsy (n=1)