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. Author manuscript; available in PMC: 2018 Nov 21.
Published in final edited form as: Nat Genet. 2018 May 21;50(6):857–864. doi: 10.1038/s41588-018-0121-0

Table 1.

Genetic correlation between immune diseases

Phenotype Asthma Allergic diseases Rheumatoid arthritis Crohn’s disease Ulcerative colitis Asthma (GABRIEL) Eczema (EAGLE)
Asthma (N=90,853) 1 0.7455 0.0942 0.0428 −0.0514 0.6649 0.4138
Allergic diseases (N=102,453) 6.84×10−62 1 0.0042 0.1415 0.0611 0.5008 0.5308
Rheumatoid arthritis (N=58,284) 0.0793 0.9259 1 0.067 0.1003 0.1001 −0.0463
Crohn’s disease (N=69,268) 0.5925 0.0371 0.318 1 0.5711 0.0604 0.1190
Ulcerative colitis (N=72,647) 0.4942 0.3721 0.1032 7.98×10−23 1 −0.0289 −0.0121
Asthma (GABRIEL) (N=26,475) 3.52×10−25 3.24×10−15 0.1312 0.5005 0.7338 1 0.5310
Eczema (EAGLE) (N=54,632) 1.29×10−9 4.04×10−15 0.5846 0.1982 0.9134 6.05×10−6 1

Upper off-diagonal shows LD score regression estimates of genetic correlation score (Rg, ranges from −1 to 1). Lower off-diagonal shows corresponding genetic correlation P value.