Table 1.
Epidemiologic and Clinical Characteristics of Patients with ISC and Without ISC
| Variables | ISCP n=46 | Non-ISCP n=573 | p value |
|---|---|---|---|
| Age, year, Mean±SD | 70.70±11.04 | 69.30±13.52 | 0.776 |
| Sex, n (%) | |||
| Female | 17 (37.0) | 273 (47.6) | 0.162 |
| Male | 29 (63.0) | 300 (52.4) | |
| Medical history | |||
| -Hypertension, n (%) | 27 (58.7) | 405 (70.7) | 0.089 |
| -Diabetes mellitus, n (%) | 17 (37.0) | 166 (29.0) | 0.253 |
| -Atrial fibrillation, n (%) | 7 (15.2) | 118 (20.6) | 0.382 |
| -Hyperlipidemia, n (%) | 2 (4.3) | 156 (27.2) | 0.001 |
| -CAD, n (%) | 10 (21.7) | 134 (23.4) | 0.799 |
| -CHF, n (%) | 3 (6.5) | 67 (11.7) | 0.287 |
| -Previous stroke history, n (%) | 8 (17.4) | 98 (17.1) | 0.960 |
| -Previous TIA history, n (%) | 4 (8.7) | 44 (7.7) | 0.804 |
| CCS classification, n (%) | |||
| -Large-artery atherosclerosis | 8 (17.4) | 144 (25.1) | 0.480 |
| -Cardio-aortic embolism | 14 (30.4) | 242 (42.2) | 0.200 |
| -Small artery occlusion | 3 (6.5) | 29 (5.1) | 0.260 |
| -Other causes | 10 (24.4) | 20 (3.9) | <0.001 |
| -Undetermined causes | 9 (19.6) | 135 (23.6) | 0.950 |
| Admission NIHSS, Median (Min-Max) | 7.5 (0.0-15.0) | 5.0 (0.0-26.0) | 0.013 |
| Recurrent stroke, n (%) | 1 (2.2) | 12 (2.1) | 0.97 |
| Mortality in hospital, n (%) | 10 (21.7) | 57 (9.9) | 0.013 |
| Follow up mRS, Median (Min-Max) | 5.0(0.0-6.0) | 1.0 (0.0-6.0) | <0.001 |
| Follow up mRS> 3, n (%) | 20 (76.9) | 117 (34.0) | <0.001 |
| Thrombocyte count/mm3, Median (Min-Max) | 218.0 (34.0-651.0) | 229.5 (6.0-877.0) | 0.529 |
| CRP mg/dl, Median (Min-Max) | 12.0 (0.0-248.0) | 8.4 (0.0-303.0) | 0.014 |
| D-dimer, Median (Min-Max) | 1,519.0 (362.0-12,487.0) | 590.5 (42.0-3,191.0) | 0.003 |
| Multiple infarct, n (%) | 16 (34.8) | 62 (10.8) | <0.001 |
ISCP, ischemic stroke patients with cancer; SD, Standard Deviation; CAD, Coronary Artery Disease; CHF, congestive heart failure; TIA, transient ischemic attack; CCS, Causative Classification System; mRS, The modified Rankin Scale; NIHSS, the National Institutes of Health Stroke Scale; CRP, C reactive protein