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The List of Central Proteins in the First NPC Network. The proteins are ranked based on degree values, which are hubs. The cut offs are designated by above 10% of the highest values of degree and betweenness (BC). Considering 10% of highest values for degree and betweenness includes five nodes for each that are also common. The cut off based on calculation for degree and BC are 9 and 0.12. Here the common nodes above the designated threshold is considered as the hub-bottlenecks.