Table 6.

The Association of the BRCA1-3’UTR-variant with Breast Cancer Risk

Genotypes	Healthy controls		Breast cancer		OR (95% CI)	RR (95% CI)	P-Value
	(N=100)	%	(N=100)	%
Co dominant
BRCA1-GG	45	(45%)	26	(26%)	1 (ref.)	1 (ref.)
BRCA1-GT	50	(50%)	66	(66%)	2.28 (1.24-4.191)	1.47 (1.11-1.93)	0.007
BRCA1-TT	5	(05%)	8	(08%)	2.76 (0.81- 9.35)	1.64 (0.81-3.35)	0.085
Dominant
BRCA1-GG	45	45%	26	26%	1 (ref.)	1 (ref.)
BRCA1 (GT+ TT)	55	55%	74	74%	2.32 (1.28- 4.22)	1.48 (1.13-1.94)	0.005
Recessive
BRCA1-(GG+GT)	100	95%	100	92.60%	1 (ref.)	1 (ref.)
BRCA1-TT	05	5%	8	7.40%	1.6 (0.506-5.05)	1.02 (0.96-0.10)	0.41
Allele
BRCA1-G	140	70%	118	59%	1 (ref.)	1 (ref.)
BRCA1-T	60	30%	82	41%	1.62 (1.072- 2.45)	1.28 (1.028- 1.60)	0.020

*OR, Odd ratio; #RR, Risk ratio