Table 2.
Comparison BRCA1 Promoter Methylation and Age, Menopausal Status, ER, PR and HER2 status (n=114)
| BRCA1 promoter methylation | p value | ||
|---|---|---|---|
| Methylation present | 68 (59.6%) | ||
| Methylation absent | 46(40.4%) | ||
| Age | BRCA1 promoter methylation | ||
| Below 50 years | 56 (49.1%) | ||
| Above 50 years | 59 (50.9%) | ||
| Menopausal status | Methylation Present | Methylation Absent | (p>0.8456) |
| Pre-menopausal 48 (42.1%) | 31 (64.6%) | 17 (35.4%) | |
| Post-menopausal 66 (57.9%) | 41 (62.1%) | 25 (37.9%) | |
| ER Expression | Methylation Present | Methylation Absent | (p>0.4068) |
| ER positive 77 (67.5%) | 47 (60.2%) | 30 (38.8%) | |
| ER negative 37 (32.5%) | 26(72.2%) | 11 (29.8%) | |
| PR Expression | Methylation Present | Methylation Absent | (p>0.5553) |
| PR positive 48 (42.1%) | 29 (60%) | 19(40%) | |
| PR negative 66 (57.9%) | 44(64.7%) | 22 (33.3%) | |
| HER 2 Expression | Methylation Present | Methylation Absent | (p>1.0000) |
| HER positive 43 (37.8%) | 27 (62.8%) | 16(37.2%) | |
| HER 2 negative 71 (62.2%) | 45 (63.3%) | 26 (36.7%) |