Table 3.
Allele and Genotype Distribution of TP53Pro72Arg SNP in Patients with Colorectal Cancer and Healthy Controls
| dbSNP | Alleles/ | Case (n=100) | Control (n=100) | P Value | Adj. P | OR (95% CI) |
|---|---|---|---|---|---|---|
| Genotypes | N (%) | N (%) | ||||
| TP53Gene Pro72Arg (rs1042522) | C | 71 (36%) | 73 (36.5%) | 0.98 | 0.98 | 0.97 (0.73-1.30) |
| G | 129 (64%) | 127 (63.5%) | 0.98 | 0.98 | 1.02 (0.76-1.36) | |
| CC (Pro/Pro) | 15 (15%) | 12 (12%) | 0.46 | 0.76 | 1.23 (0.69-2.17) | |
| GC (Arg/Pro) | 41 (41%) | 48 (48%) | 0.52 | 0.24 | 0.78 (0.52-1.16) | |
| GG (Arg/Arg) | 44 (43%) | 40 (40%) | 0.87 | 0.47 | 1.15 (0.77-1.71) | |
| HWE | 0.56 | 0.66 |
HWE, Hardy–Weinberg Equilibrium