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. 2018;19(2):513–519. doi: 10.22034/APJCP.2018.19.2.513

Table 4.

Difference in Expression of Cyclin D1 and HnRNA Parameters in Urothelial Carcinoma (UC) in Relation to Tumor Grade, Muscle Invasion, Papillary Pattern and Bilharzial Association

Parameter Cyclin D1 HnRNA
(n) percent intensity score percent intensity score
Tumor Grade
 High grade Mean 35.1 1.81 1.84 80.75 2.51 202.13
 (26) S.D 29.41 0.83 0.91 10.85 0.5 46.55
 Low Grade Mean 50.62 2 2.37 25.12 1.5 45
 (40) S.D. 32.5 0.63 0.71 15.49 0.52 36.15
 p value (t-test) N.S N.S <0.05 <0.00 <0.00 <0.00
Muscle invasion
 Negative Mean 69.29 2.86 2.71 43.33 1.83 98.33
 (42) S.D 20.46 0.36 0.47 29.88 0.7 90.87
 Positive Mean 36.88 1.63 2.06 79.35 2.44 190.8
 (24) S.D. 26.01 0.49 0.67 10.92 0.49 36.45
 p value (t-test) < 0.001 < 0.001 < 0.01 <0.00 <0.00 <0.00
Papillary pattern
 Non-papillary Mean 37.33 1.6 2.13 82.5 2.6 213.12
 (38) S.D 27.85 0.49 0.73 13.17 0.49 47.35
 Papillary Mean 64.38 2.75 2.5 47.86 2.01 115.71
 (28) S.D. 20.89 0.45 0.52 29.42 0.77 92.23
 p value (t-test) < 0.01 < 0.001 < 0.05 <0.00 <0.00 <0.00
Bilharzial Association
 Negative Mean 46.59 2.05 2.27 66.05 2.32 163.42
 (54) S.D 29.19 0.75 0.69 27.54 0.66 81.39
 Positive Mean 50.76 2.11 2.09 78.35 2.2 171.87
 (12) S.D. 0.46 0.19 0.01 5.37 0.42 30.26
 p value (t-test) N.S. N.S. N.S. <0.05 N.S. N.S.

S.D, standard deviation