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GHTg mice are resistant to collagen-induced arthritis. One representative experiment is shown of three performed (n = 11 mice/group). (A) Cumulative incidence of arthritic symptoms in wild-type (wt) and GHTg mice after immunization with chicken type II collagen. (B) Clinical scores in affected wt and GHTg mice. Data shown as mean ± SEM (Student’s t-test, *p ≤ 0.05). Two-way ANOVA shows significant differences for time (p = 0.0217) and genotype (p < 0.0001) factors.
