Table 2.
Comparison of demographic and clinical characteristics between those with (serum B12 <133 pmol/l) and without B12 deficiency.
| B12 deficiency |
|||||
|---|---|---|---|---|---|
| Yes (n = 32) | No (n = 330) | P value | |||
| Demographics | |||||
| Metformin (%) | 60 | 80 | 0.03 | ||
| Age (years) | 49.16 | (9.72) | 54.56 | (12.71) | 0.01 |
| Diabetes duration (years) | 7.03 | (5.39) | 11.68 | (7.89) | <0.001 |
| SBP (mmHg) | 127.42 | (15.47) | 131.22 | (19.58) | 0.21 |
| DBP (mmHg) | 77.93 | (11.32) | 76.95 | (9.72) | 0.66 |
| BMI (kg/m2) | 31.39 | (6.48) | 32.16 | (7.60) | 0.55 |
| HbA1c (%) | 7.76 | (1.97) | 7.99 | (1.92) | 0.52 |
| Total cholesterol (mmol/l) | 4.30 | (1.04) | 4.47 | (1.14) | 0.39 |
| Triglycerides (mmol/l) | 1.53 | (0.91) | 1.77 | (1.07) | 0.19 |
| HDL (mmol/l) | 1.07 | (0.41) | 1.08 | (0.34) | 0.94 |
| LDL (mmol/l) | 2.61 | (0.84) | 2.49 | (0.87) | 0.49 |
| Neuropathy assessments | |||||
| DPN (%) | 32 | 33 | 0.85 | ||
| VPT (V) | 11.87 | (9.51) | 12.65 | (9.19) | 0.62 |
| Neuropathic pain (%) | 31 | 32 | 0.79 | ||
| DN4 | 2.47 | (2.98) | 3.04 | (2.59) | 0.27 |
Data are presented as mean SD. Unpaired t- and χ2 tests were used to compare continuous and categorical data, respectively between the groups.
SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, Body mass index; DPN, Diabetic peripheral neuropathy; VPT, vibration perception threshold; DN4, neuropathic pain diagnostic questionnaire.