Results from Externally Cued Action Control Task
(A) Participants were asked to join the bottom circle to as many target circles as possible in 90 s. Only one target, which was always red in color, appeared at a time. It turned gray after being touched, and then a new red target appeared. Thus, this task does not require either option generation or selection but requires motor planning of a different action each time.
(B) In healthy people (n = 30), there was a significant correlation between fluency in the option-generation task and individual level of motivation even after regressing out the number of targets hit in this control task.
(C) In PD (n = 35), the change in fluency in the option-generation task between the ON and OFF states did not relate to the change in the number of targets hit on the externally cued action control task.
(D) In healthy elderly people (n = 29), the difference in option generation fluency when on cabergoline and placebo also did not relate that in motor planning ability. This indicates that reductions in fluency of option generation when PD patients are OFF dopamine and when healthy people are on placebo is not explained simply by deficits in planning or initiating actions.
See also Figures S6 and S7.