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Restriction of the dermonecrotic area and the severity of dermonecrosis at days 3, 5, and 7 in the mouse model. Images of the dermonecrotic areas in the medium control-, CPPTat-JDlys-, JDlys-, and Cm-treated mice are shown and are representative of those from three experiments. Note the smaller areas of dermonecrosis and the faster healing of lesions in CPPTat-JDlys-treated mice than in the control mice, in which the lesions remained exudative.
