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Targets of nitrite and NO in S. oneidensis and E. coli. (A) Effects of overproduction of SoAcnB and SoLpdA on growth of S. oneidensis. (B) Effects of nitrite and NO on activity of putative targets in S. oneidensis. Enzyme activities in cell extracts with increasing concentrations of NO, released by DEA-NONOate, or nitrite were determined. Percent activity is normalized to unexposed cell extracts. Data are shown as means ± SEMs from at least three experiments.
