Table 1.

Thermodynamic parameters for binding of dUMP to TSase^a.

T (°C)	K1 × 104 (M−1)b	K2 × 104 (M−1)	Δ${\text{H}}_1^{°}$ (kcal/mol)	Δ${\text{H}}_2^{°}$ (kcal/mol)	ρ
5	7.7 ± 0.8	6.2 ± 1.0	−1.2 ± 0.01	−0.58 ± 0.01	0.80 ± 0.06
25c	6.0 ± 0.1	5.9 ± 0.1	−4.5 ± 0.01	−4.4 ± 0.02	0.98 ± 0.08

^aData from Sapienza et al. (2015), Conditions are 25 mM NaPO4, 1 mM EDTA, 2 mM TCEP.

^bIntrinsic binding constants from fits to the modified general model.

^cMean and standard deviations from multiple samples; including global fits of multiple c-value datasets (e.g., Figure 3A).