Table 1.
Genome-wide significant (p < 5*10E-08) and suggestive (p < 5*10E-06) associations with VPD.
| Locus | SNP | Chr | BP position | P | A1 | A2 | MAF | Annotated genes |
|---|---|---|---|---|---|---|---|---|
| 3p24.3 | rs13095954 | 3 | 18108126 | 1.05E-07 | G | C | 0.07358 | SATB1 |
| 3q29 | rs6583326 | 3 | 196317308 | 2.86E-08 | T | C | 0.1434 | TFRC, PCYT1A |
| 4q22.3 | rs11727234 | 4 | 96807975 | 6.95E-07 | G | T | 0.05155 | — |
| 5p13.1 | rs56276612 | 5 | 40427385 | 1.19E-07 | T | G | 0.09129 | — |
| 6p12.2 | rs10948810 | 6 | 54176227 | 4.08E-07 | C | T | 0.05169 | — |
| 6q26 | rs3900809 | 6 | 161135202 | 2.94E-07 | G | A | 0.05169 | MAP3K4, PARK2 |
| 8q21.2 | rs34927688 | 8 | 8622794 | 7.59E-07 | G | A | 0.07439 | — |
| 9p21.1 | rs2800342 | 9 | 30183553 | 4.88E-08 | T | A | 0.05983 | — |
| 9p22.2 | rs1538101 | 9 | 16710870 | 3.39E-07 | G | A | 0.05169 | BNC2 |
| 9p22.3 | rs72702916 | 9 | 14484998 | 1.47E-07 | C | G | 0.07164 | FREM1 |
| 11q25 | rs56160206 | 11 | 133921939 | 8.02E-08 | CA | C | 0.1263 | GLB1L2, B3GAT1 |
| 12q21.31 | rs1133104 | 12 | 8291122 | 1.96E-08 | G | T | 0.1712 | — |
| 14q13.1 | rs73257280 | 14 | 32270651 | 6.48E-07 | C | CT | 0.05113 | — |
| 14q23.3 | chr14:66527789 | 14 | 66527789 | 4.48E-07 | T | A | 0.05236 | — |
| 16p12.1 | rs77085399 | 16 | 22002367 | 9.89E-07 | C | T | 0.16 | — |
| 16p12.3 | rs12922822 | 16 | 20367645 | 2.08E-08 | T | C | 0.1498 | — |
| 16p13.3 | rs13335236 | 16 | 4955256 | 3.50E-09 | C | T | 0.05733 | NAGPA, RBFOX1 |
| 18q21.32 | rs11877326 | 18 | 56503556 | 2.64E-07 | A | G | 0.07174 | — |
| 18q22.1 | rs66549549 | 18 | 62628423 | 4.39E-07 | T | G | 0.05215 | — |
| 22q12.1 | rs9613645 | 22 | 28947402 | 7.57E-08 | T | A | 0.08383 | TTC28, KREMEN1 |