Fig. 1. Biosynthetic pathway of the common precursor to BIAs in plants.

The dash line indicates unknown reaction. TYDC tyrosine/DOPA decarboxylase, NCS norcoclaurine synthase, 6OMT norcoclaurine 6-O-methyltransferase, CNMT (S)-coclaurine N-methyltransferase, CYP80B, (S)-N-methylcoclaurine 3′-hydroxylase, 4′OMT 3′-hydroxy-N-methylcoclaurine 4′-O-methyltransferase