. 2018 Apr 10;3(4):197–213. doi: 10.1159/000485800

Table 10.

Comparison of Affymetrix and NanoString results showing that the Affymetrix exon array had higher sensitivity and specificity for prediction

NanoString probeset ID	Genes included in each predictive model
	NC vs. SZ/BD		NC vs. SZ		NC vs. BD		SZ vs. BD
	Affymetrix ID	NanoString	Affymetrix ID	NanoString	Affymetrix ID	NanoString	Affymetrix ID	NanoString
2537112_SH3YL1 (30)		x		x		x		x

2537128_SH3YL1 (61)				x		x		x

2647124_CPA3 (65)		x		x		x		x

2647119_CPA3 (69)	2647109	x		x		x		x

3554833_CRIP2 (68)		x				x	3554818

2418590_SLC44A5 (51)	2418570	x	2418570	x

2661997_OXTR (43)	2661992				2661992	x	2661992	x

2906733_TREML4 (62)	2906720			x

3063538_TRIM4 (52)	3063536	x		x		x

2723770_TBC1D1 (55)								x

3195045_PTGDS (59)	3195034	x		x	3195034	x		x

2401362_TCEA3 (70)			2401347					x

3667896,97_HPR	3667890

3908171_ZMYND8	3908149

2545100_HADHA	2545092

2739191_CCDC109B	2739160

3846545_EEF2	3846538

3333251,56,58,62,69,70,74_FADS2					3333247		3333247

4048243,52_HLA-DRB5					4048241

3329128_GYLTL1B			3329099

2660633,41_IL5RA			2660617

3766938_DDX5			3766893

AUC¹	0.994	0.913	0.954	0.990	0.974	0.953	0.998	0.905

Visit 2 sensitivity	93.3%	98.3%	96.7%	96.6%	96.7%	89.3%	96.7%	86.2%

Visit 2 specificity	100%	75.0%	83.3%	96.4%	86.7%	92.9%	100%	82.1%

Visit 4 sensitivity	96.7%	87.5%	100%	75.0%	93.3%	75.0%	96.7%	57.1%

Visit 4 specificity	93.3%	60.0%	80%	80.0%	100.0%	76.0%	100%	85.7%

Visit 2/4 agreement	93.3%	77.6%	86.7%	76.0%	88.3%	75.5%	100%	64.2%

BD, bipolar disorder; SZ, schizophrenia; NC, normal control.

The AUC was for combined visit 2 and 4 modeling, and each visit was evaluated for predictions individually.