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. 2018 Apr 10;3(4):197–213. doi: 10.1159/000485800

Table 6.

The 18-gene signature was extracted from an independent data set of gene expression data and analyzed by the same logistic regression equations as derived from the fit to our original data

Subjects NC, n SZ, n ROC AUC Sensitivity Specificity
Antipsychotic free (all subjects) 22 15 0.642 80.00% 59.10%
Antipsychotic free (subjects aged <30 years) 14 8 0.866 100.00% 71.40%

Using this data set from antipsychotic-free SZ subjects, the 18-gene diagnostics produced a ROC accuracy of 0.866 in medication-free patients below 30 years of age. The classification of antipsychotic-free patients with SZ was made using data from the Illumina HT-8 array [6]. SZ, schizophrenia; NC, normal control.