Table 6.
Subjects | NC, n | SZ, n | ROC AUC | Sensitivity | Specificity |
---|---|---|---|---|---|
Antipsychotic free (all subjects) | 22 | 15 | 0.642 | 80.00% | 59.10% |
Antipsychotic free (subjects aged <30 years) | 14 | 8 | 0.866 | 100.00% | 71.40% |
Using this data set from antipsychotic-free SZ subjects, the 18-gene diagnostics produced a ROC accuracy of 0.866 in medication-free patients below 30 years of age. The classification of antipsychotic-free patients with SZ was made using data from the Illumina HT-8 array [6]. SZ, schizophrenia; NC, normal control.