Table 9.
Summary of NanoString cut-point diagnostic accuracy
| Significant probesets1 | NC vs. SZ/BD | NC vs. SZ | NC vs. BD | SZ vs. BD |
|---|---|---|---|---|
| 2537112_SH3YL1 (30) | x | x | x | x |
| 2537128_SH3YL1 (61) | x | x | x | |
| 2647124_CPA3 (65) | x | x | x | x |
| 2647119_CPA3 (69) | x | x | x | x |
| 3554833_CRIP2 (68) | x | x | ||
| 2418590_SLC44A5 (51) | x | x | ||
| 2661997_OXTR (43) | x | x | ||
| 2906733_TREML4 (62) | x | |||
| 3063538_TRIM4 (52) | x | x | x | |
| 2723770_TBC1D1 (55) | x | |||
| 3195045_PTGDS (59) | x | x | x | x |
| 2401362_TCEA3 (70) | x | |||
| AUC | 0.913 | 0.990 | 0.953 | 0.905 |
| Visit 2 sensitivity | 98.3% | 96.6% | 89.3% | 86.2% |
| Visit 2 specificity | 75.0% | 96.4% | 92.9% | 82.1% |
| Visit 4 sensitivity | 87.5% | 75.0% | 75.0% | 57.1% |
| Visit 4 specificity | 60.0% | 80.0% | 76.0% | 85.7% |
| Visit 2/4 agreement | 77.6% | 76.0% | 75.5% | 64.2% |
BD, bipolar disorder; SZ, schizophrenia; NC, normal control.
1
Format as explained in Table 8.